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1,2-propanediol biosynthesis from lactate (engineered)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
acetyl-CoA + L-lactate <=> acetate + lactoyl-CoA 2.8.3.1 propionate CoA-transferase

(S)-1,2-Propanediol + NADP+ <=> L-lactaldehyde + NADPH + H+ 1.1.1.55 lactaldehyde reductase (NADPH)

acetyl-CoA + D-lactate <=> acetate + (R)-lactoyl-CoA 2.8.3.1 propionate CoA-transferase

(R)-1,2-Propanediol + NADP+ <=> D-Lactaldehyde + NADPH + H+ 1.1.1

L-lactaldehyde + CoA + NAD+ <=> lactoyl-CoA + NADH + H+ 1.2.1.87 propanal dehydrogenase (CoA-propanoylating)

D-Lactaldehyde + CoA + NAD+ <=> (R)-lactoyl-CoA + NADH + H+ 1.2.1.87 propanal dehydrogenase (CoA-propanoylating)

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